I used Teamine for the first time in 2007. I have hereditary dark circles and noticed about a 70% reduction in the darkness within 4 weeks of use. After using it for another few months, they were reduced to about 80%. I was able to get away without wearing concealer, only using a light touch of MAC powder over my entire face. I stopped using it because I thought I was “cured” and no longer needed it! Wrong! This is a maintenance product. I started using it again a couple of weeks ago. I will report back in a couple of months.