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For decades, skincare has focused on surface-level concerns—fine lines, uneven tone, dryness—without addressing the deeper biological changes that determine how skin ages over time. At Revision Skincare®, we believe true skin longevity starts beneath the surface, at the structural and cellular level where skin function is defined.
That’s why our innovation is centered on the Longevity Layer™, scientifically known as the Dermal-Epidermal Junction (DEJ)—the critical interface responsible for communication between the epidermis and dermis. As this layer weakens with age, nearly every visible sign of aging accelerates.
By targeting the DEJ, Revision Skincare® isn’t just improving how skin looks today—we’re supporting how it functions for years to come.
Why Skin Longevity Matters
Traditional “anti-aging” focuses on correcting visible damage after it appears. Skin longevity takes a fundamentally different approach. It asks:
How do we support skin so it can function better, adapt longer, and age more slowly over time?
Longevity science has identified 12 biological hallmarks of aging—core processes that influence how cells behave as they age. These hallmarks impact every organ in the body, but the skin is the only one where their effects are visible.
At Revision Skincare®, we’ve identified which of these hallmarks skincare has the unique power to influence—and we’ve built our formulas to do exactly that.
The Three Hallmarks of Aging That Matter Most for Skin
While all 12 hallmarks play a role in aging, three are especially critical to visible skin longevity—and all three converge at the DEJ.
1. Cellular Communication
As skin ages, communication between cells slows and becomes less efficient. At the DEJ, this breakdown leads to reduced collagen and elastin production, weakened structure, and visible loss of firmness.
Revision Skincare® formulas within our DEJ family, including D·E·J Face Cream®, D·E·J Eye Cream®, and D·E·J Daily Boosting Serum™, are designed to help support more youthful signaling—strengthening the connection between skin layers for improved resilience and visible rejuvenation.
2. Mitochondrial Function (Cellular Energy)
Mitochondria are the powerhouses of skin cells, fueling repair, regeneration, and collagen synthesis. As mitochondrial function declines with age, skin loses energy—appearing dull, fatigued, and slower to recover.
D·E·J Daily Boosting Serum™ was developed to help support mitochondrial energy and improve skin’s ability to resist and recover from daily stressors. This targeted energy support helps restore visible vitality while strengthening skin over time.
This is the “E” in our ABC+E philosophy—Energy as a foundational pillar of skin longevity.
3. Microbiome Balance
The skin’s microbiome is a living ecosystem that plays a critical role in barrier integrity, inflammation regulation, and overall resilience. As we age, this balance becomes more fragile, often contributing to sensitivity, dehydration, and impaired repair.
From Intellishade® to BodiContour™ to our DEJ family, many Revision Skincare® formulas incorporate postbiotic and microbiome-supporting ingredients, along with thoughtfully selected actives like bakuchiol, to help maintain balance while delivering visible results.
By respecting the microbiome, we help create an environment where skin can function optimally—now and long term.
The Longevity Layer™ (DEJ): Where Longevity Begins
The DEJ is where:
- Cellular communication directs collagen and elastin production
- Mitochondrial energy supports repair and renewal
- Microbiome balance helps maintain barrier strength
When the DEJ is supported, skin behaves younger.
When it deteriorates, aging accelerates.
This is why Revision Skincare® leads with Longevity Layer™ science—because strengthening the DEJ means strengthening the biological foundation of youthful skin.
The Revision Formula for Skin Longevity
At Revision Skincare®, longevity isn’t a trend—it’s a formula.
Targeting root causes + bioavailable actives + multiple pathways + microbiome respect + skin-neutral pH + synergistic formulation = Skin Longevity.
We didn’t follow the formula.
We defined it.
The Future of Skin Longevity Starts Here
Skin longevity isn’t about chasing trends or quick fixes. It’s about strengthening the systems that keep skin healthy, resilient, and youthful over time.
And it all starts at the Longevity Layer™.
Welcome to the future of skincare.
Welcome to Revision Skincare®.
